Dong Quai
INCI: Dong Quai (Angelica sinensis)
Dong Quai (Angelica sinensis) is a traditional Chinese herbal root used in food supplements for women's wellness and circulation support. It is classified as a botanical on the EFSA on-hold list, meaning no EU-authorised health claims are available. Brands typically position it with general wellness language or through traditional herbal registration routes.
- herbal-wellness
- womens-health
- circulation-support
At a glance
- Definition
- Dong Quai (Angelica sinensis) is a traditional Chinese herbal root used in food supplements for women's wellness and circulation support. It is classified as a botanical on the EFSA on-hold list, meaning no EU-authorised health claims are available. Brands typically position it with general wellness language or through traditional herbal registration routes.
- Authorised wording (summary)
- 2 authorised statements — see "US structure-function statements" below.
- Common positionings
- Women's cycle support
- Circulation & vitality
- Traditional herbal wellness
- Hormonal balance support
- Energy & blood nourishment
- Format suitability
- Reviewed for gummies and sachets — confirmed per project.
Where this ingredient fits in the DAT Supply catalogue
Every format chip links through to its manufacturing hub and to the private-label catalogue for that format. The category chip routes to the matching vertical hub on the categories index.
- Botanicals & mushrooms
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What it is
Dong Quai, also known as Angelica sinensis or Female Ginseng, is a perennial herb native to China whose root has been used in traditional Chinese medicine for over two thousand years. It is one of the most recognised botanicals in women's health supplementation, valued for its traditional association with menstrual cycle support and blood nourishment.
For private-label brands, Dong Quai offers a well-known herbal positioning that resonates with consumers seeking natural approaches to hormonal balance and vitality. Because it is a botanical on the EFSA on-hold list, brands must be disciplined about claim language — general wellness and traditional-use positioning are the primary routes for EU markets.
Origin and history
Dong Quai has been cultivated and used in China for millennia, primarily in the regions of Gansu, Sichuan, and Yunnan. It is a cornerstone herb in traditional Chinese medicine, where it is classified as a blood-tonifying herb and used in formulas for gynaecological health. The root is harvested after two to three years of growth, then dried and processed for medicinal use.
Industrial production of Dong Quai extract involves drying the root, milling it, and extracting with ethanol or water to produce a standardised extract. The key active compound, ligustilide, is used as a marker for standardisation. Modern manufacturing focuses on consistent quality and batch-to-batch reproducibility, which is essential for supplement production.
Scientific overview
Dong Quai contains a range of bioactive compounds including ligustilide, ferulic acid, and various coumarins. Ligustilide is considered the primary active constituent and has been studied for its effects on smooth muscle relaxation and blood circulation. Ferulic acid is a phenolic compound with antioxidant properties. The traditional use of Dong Quai for women's health is thought to relate to its influence on uterine muscle tone and blood flow.
Bioavailability of Dong Quai's active compounds varies. Ligustilide is lipophilic and may be better absorbed with dietary fat. Standardised extracts provide more consistent dosing than whole root powder. The choice between extract and powder affects both cost and formulation flexibility in gummies.
From a manufacturing perspective, Dong Quai is heat-stable and soluble in gummy formulations, making it a practical choice for gummy production. The earthy, aromatic taste requires moderate masking — fruit flavours such as berry, cherry, or citrus work well. Cost per serving is mid-tier, making it accessible for brands targeting the women's wellness segment.
Why brands use Dong Quai
Dong Quai is one of the most familiar botanicals in women's health supplementation, and gummies offer a convenient, palatable format that appeals to consumers who prefer not to swallow capsules. The positioning landscape includes cycle support, vitality, and traditional herbal wellness. Brands often pair Dong Quai with Vitex or Vitamin E to create a comprehensive women's wellness formula.
From a formulation perspective, Dong Quai is well-suited to gummy manufacturing. It is heat-stable and soluble, and the earthy taste can be effectively masked with fruit flavours. The mid-tier cost makes it viable for both white-label and custom development. DAT confirms the final formulation, dosing, and taste profile per project.
For pack copy, brands must be disciplined. Because Dong Quai has no authorised EU health claims under Reg. 432/2012, claim language must be limited to general wellness or traditional-use positioning. DAT reviews claim strategy per project and market to ensure compliance. No disease claims, no "anti-inflammatory," and no certification promises on pack until confirmed per project and batch.
Formats this ingredient is reviewed for
DAT Supply covers gummy, capsule, softgel, tablet, powder, oral strip, liquid drop, shot, jelly and pet formats. The list below reflects every format this ingredient is reviewed for — chips link through to the manufacturing hub for each format. Final compatibility, dose and matrix are confirmed per project.
Formulation notes
Verified formulation reference across the formats this ingredient is reviewed for — the Supported formats section lists every product format this active is approved for, and the per-format Considerations section below covers matrix-specific guidance. Final formulation, dose and on-pack copy are confirmed per project.
- Gummy fit
- Good
- Heat stable
- Yes
- Soluble in matrix
- Yes
- Cost tier
- Medium
Forms available
- Dried root extract (standardised to ligustilide), powdered root
Dosage reference
Typical brand positioning range is 200–1500 mg per serving. No reference-intake target reviewed per market established for botanicals. DAT confirms the final dose per project based on target market and claim strategy.
Taste & sensory
Aromatic earthy. Moderate masking required in gummies — fruit flavours such as berry or citrus work well.
Manufacturing notes
Gummy-optimized dosing and format considerations. Standardised extracts help maintain batch consistency in gummy production.
Per-format formulation notes
Safe-baseline considerations for each format this ingredient is reviewed for. Final formulation, dose and on-pack copy are confirmed per project.
Gummies
- Taste masking and aroma load against the cooked-base flavour — confirmed per project.
- Heat exposure during cooking; coated or encapsulated forms may be required — confirmed per project.
- Matrix choice (pectin vs gelatin) and its effect on ingredient stability — confirmed per project.
- Per-gummy dose and serving count needed to hit the label claim — confirmed per project.
Sachets
- Powder flow and dose accuracy at single-serve sachet weights — confirmed per project.
- Barrier requirements (oxygen, moisture) for the active — confirmed per project.
- Reconstitution behaviour when the sachet is dosed into water — confirmed per project.
US structure-function statements
- Supports women's health and vitality.Structure-function (DSHEA)
- Traditionally used to support blood circulation.Structure-function (DSHEA)
Structure-function statements must appear with the FDA disclaimer in the same field of vision on the label. % Daily Value (DV) based on FDA 21 CFR 101.9.
Wording to avoid on pack copy
- No disease claims — this product is not intended to diagnose, treat, cure, or prevent any disease.
- Structure-function claims must be accompanied by the FDA disclaimer: 'These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.'
- No certification promises on pack until confirmed per project and batch documentation.
- No guaranteed shelf-life until confirmed with stability data.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Structure-function claims are permitted under DSHEA (21 USC §343(r)(6)). No Daily Value (DV) has been established for Dong Quai under FDA 21 CFR 101.9.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Studies & evidence
External peer-reviewed sources and regulatory opinions. Citations only — DAT does not endorse the publishers.
Yin, J., et al.·Journal of Ethnopharmacology·2020
Zhang, Y., et al.·Phytotherapy Research·2019
Kumar, N., et al.·Food and Chemical Toxicology·2018
EFSA Panel on Food Additives·EFSA Journal·2012
Product concepts featuring Dong Quai
Private-label product concepts where Dong Quai appears in the formula. Each opens to a product brief and quote route.
Desire & Vitality Gummies
Private label desire & vitality gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Perimenopause Support Gummies
Private label perimenopause support gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Synergies & conflicts
Pairs well with
Pairs with Vitex (hormonal balance) and Vitamin E (blood circulation).
Care when combining with
Photosensitivity possible. Not well-studied in pregnancy — traditional use only. DAT reviews per project for contraindications with other active ingredients.
Similar ingredients
Ingredients that frequently sit alongside this one in private-label supplement briefs.

Aloe Vera
Aloe Vera (Aloe barbadensis) is a succulent plant whose inner gel is used in food supplements for its hydrating and soothing properties. As a botanical on the EU on-hold list, it carries no authorised health claims under Reg. 432/2012. Brands typically position it around general wellness, digestive comfort, and skin hydration, often co-formulated with Vitamin C or probiotics for claim support.

Artichoke
Artichoke (Cynara scolymus) is a botanical ingredient used in dietary supplements for its traditional association with digestive and liver function. It is one of the most familiar and commercially understood botanical actives across EU and US markets. As a botanical on the EU on-hold list, no authorised health claims are currently permitted under Reg. 432/2012.

Arugula Extract
Arugula extract is a botanical ingredient derived from Eruca sativa leaves, used in gummy and sachet formats for green superfood and daily wellness positioning. It is a botanical on the EFSA on-hold list with no authorised health claims under Reg. (EU) 432/2012. Any claim coverage must come from co-formulated nutrients.

Ashwagandha
Ashwagandha (Withania somnifera) is a traditional Ayurvedic root used historically for stress, vitality, and sleep. In gummy formats it is most commonly positioned within stress-and-calm or sleep stacks. Ashwagandha sits on the EFSA "on-hold" list of botanical claims, with no authorised EU health claims of its own; substantiated claim wording in Ashwagandha gummies typically derives from co- formulated nutrients such as Magnesium and Vitamin B6.

Bacopa Extract
Bacopa Extract (Bacopa monnieri) is a botanical ingredient traditionally used in Ayurvedic wellness systems. In private-label gummy manufacturing, it is positioned for cognitive support, memory, and stress resilience. Bacopa has no EFSA-authorised health claims under Reg. 432/2012; claim coverage for cognitive function relies on co-formulated nutrients such as Vitamin B6, B12, or Iron.

Bamboo Extract
Bamboo extract is a plant-derived ingredient standardised for silica content, sourced from Bambusa vulgaris. It is used in gummy and sachet formulations as a natural source of silicon, a mineral involved in connective tissue structure. Under applicable claims framework, bamboo extract carries no authorised health claims; brands typically co-formulate with Biotin, Zinc, or Vitamin C for hair, skin, and nails positioning.
Adjacent reading
Pairings, resource guides and blog notes most often associated with Dong Quai on DAT Supply briefs.
Common pairings
Ingredients that frequently co-formulate with Dong Quai.
Develop a formula featuring Dong Quai
A ready white-label formula exists — open a product brief, or talk to our team to align the launch plan.