Maitake Extract
INCI: Grifola frondosa extract
Maitake (Grifola frondosa) is a culinary-medicinal mushroom native to Japan and North America, used in traditional mushroom blends for general wellness and vitality. As a botanical ingredient on the EFSA on-hold list, it carries no authorised EU health claims under Reg. 432/2012. Brands typically position it within immune support, daily wellness, and healthy ageing ranges, often co-formulated with Vitamin C, Vitamin D, or Zinc to support claimable benefits.
- daily wellness
- immune support
- healthy ageing
At a glance
- Definition
- Maitake (Grifola frondosa) is a culinary-medicinal mushroom native to Japan and North America, used in traditional mushroom blends for general wellness and vitality. As a botanical ingredient on the EFSA on-hold list, it carries no authorised EU health claims under Reg. 432/2012. Brands typically position it within immune support, daily wellness, and healthy ageing ranges, often co-formulated with Vitamin C, Vitamin D, or Zinc to support claimable benefits.
- Authorised wording (summary)
- 2 authorised statements — see "US structure-function statements" below.
- Common positionings
- immune support
- daily wellness
- vitality
- healthy ageing
- stress resilience
- Format suitability
- Reviewed for gummies and sachets — confirmed per project.
Where this ingredient fits in the DAT Supply catalogue
Every format chip links through to its manufacturing hub and to the private-label catalogue for that format. The category chip routes to the matching vertical hub on the categories index.
- Botanicals & mushrooms
- Browse all ingredients
What it is
Maitake, also known as Grifola frondosa, hen of the woods, or cloud mushroom, is a polypore fungus that grows at the base of oak trees. It has been used in East Asian traditional wellness systems for centuries and is now one of the most commercially recognised functional mushroom ingredients in the EU and US supplement markets. The extract is standardised to polysaccharide content, typically beta-glucans, which provide batch-to-batch consistency for manufacturing.
For private-label brands, maitake offers a familiar, consumer-trusted ingredient with broad positioning flexibility. It works well in gummy formats because the extract is heat-stable, soluble, and carries a mild umami flavour that blends easily with fruit profiles. Brands use it in daily wellness gummies, immune support blends, and multi-mushroom formulations alongside reishi, lion's mane, and shiitake.
Origin and history
Maitake has been foraged and cultivated in Japan for over a thousand years, where its name means "dancing mushroom" — reportedly because people would dance with joy upon finding it in the wild. It grows naturally in temperate forests of Japan, China, and eastern North America, typically at the base of oak, elm, and maple trees. Commercial cultivation began in Japan in the 1980s and has since expanded to controlled indoor production worldwide.
Industrial production of maitake extract involves cultivating the mycelium on a substrate, harvesting the fruiting bodies, drying them, and extracting the bioactive compounds using hot water or ethanol. The resulting extract is standardised to a specified polysaccharide content, typically 30–50% beta-glucans, and spray-dried into a fine powder suitable for gummy and sachet manufacturing. Most commercial supply originates from China, Japan, and the United States.
Scientific overview
Maitake contains a range of bioactive compounds, most notably beta-glucan polysaccharides, which are the primary marker compounds used for standardisation. These polysaccharides are recognised by immune cells in the gut-associated lymphoid tissue, where they modulate signalling pathways involved in the body's natural defence responses. The beta-glucan content is the key quality parameter for commercial extracts.
Bioavailability of maitake polysaccharides is limited by molecular weight — larger beta-glucans are poorly absorbed but still exert effects through gut-immune interaction. Some extracts use enzymatic hydrolysis to reduce molecular weight and improve solubility, though this is not standard across all supply chains. The whole fruiting body powder provides a broader phytochemical profile but lower polysaccharide concentration per gram compared to standardised extracts.
Manufacturing watchpoints include verifying the polysaccharide standardisation method (HPLC vs. UV-Vis), confirming heavy metal compliance with EU limits (Commission Regulation 1881/2006), and ensuring the extract is free from adulterants such as starch or grain fillers. Heat stability is good for gummy processing, and the extract dissolves readily in the aqueous phase of the gummy slurry.
Why brands use Maitake Extract
Maitake is one of the most familiar and commercially understood functional mushroom actives across EU and US markets. Consumer awareness of medicinal mushrooms has grown significantly, and maitake sits alongside reishi and lion's mane as a core ingredient in mushroom blend gummies. Brands position it within daily wellness, immune support, and healthy ageing ranges, often targeting consumers who prefer plant-based, adaptogenic ingredients over synthetic alternatives.
From a formulation perspective, maitake extract is well-suited to gummy manufacturing. It is heat-stable, soluble in water, and carries only a mild umami flavour that is easily masked by berry, citrus, or tropical fruit profiles. The cost per serving is moderate, making it accessible for mid-tier private-label ranges. Standardised extracts at 30–50% polysaccharides provide consistent dosing and batch reproducibility.
Pack-copy discipline is essential for EU markets. Because maitake is on the EFSA on-hold list, no specific health claims are authorised. Brands must avoid disease claims and the term "anti-inflammatory" in consumer-facing copy. Immune support positioning is possible when co-formulated with Vitamin C, Vitamin D, or Zinc, which carry authorised claims under Reg. 432/2012. DAT reviews all claim wording per project to ensure compliance with EU and UK regulations.
Formats this ingredient is reviewed for
DAT Supply covers gummy, capsule, softgel, tablet, powder, oral strip, liquid drop, shot, jelly and pet formats. The list below reflects every format this ingredient is reviewed for — chips link through to the manufacturing hub for each format. Final compatibility, dose and matrix are confirmed per project.
Formulation notes
Verified formulation reference across the formats this ingredient is reviewed for — the Supported formats section lists every product format this active is approved for, and the per-format Considerations section below covers matrix-specific guidance. Final formulation, dose and on-pack copy are confirmed per project.
- Gummy fit
- Good
- Heat stable
- Yes
- Soluble in matrix
- Yes
- Cost tier
- Medium
Forms available
- powdered extract (polysaccharide-standardised)
- liquid extract
- whole fruiting body powder
Dosage reference
Brand positioning typically ranges from 500 mg to 3000 mg per serving. reference-intake target reviewed per market not established for mushroom extracts. DAT confirms final dosage per project based on target market, claim strategy, and regulatory review.
Taste & sensory
Mild umami flavour that blends well in gummy formulations with fruit flavours. Typically masked by berry or citrus profiles at standard inclusion rates.
Manufacturing notes
Mushroom extracts require polysaccharide-standardised raw material for batch consistency. Probiotics require separate manufacturing and shelf-life considerations — do not co-formulate with live cultures in the same gummy without stability testing.
Per-format formulation notes
Safe-baseline considerations for each format this ingredient is reviewed for. Final formulation, dose and on-pack copy are confirmed per project.
Gummies
- Taste masking and aroma load against the cooked-base flavour — confirmed per project.
- Heat exposure during cooking; coated or encapsulated forms may be required — confirmed per project.
- Matrix choice (pectin vs gelatin) and its effect on ingredient stability — confirmed per project.
- Per-gummy dose and serving count needed to hit the label claim — confirmed per project.
Sachets
- Powder flow and dose accuracy at single-serve sachet weights — confirmed per project.
- Barrier requirements (oxygen, moisture) for the active — confirmed per project.
- Reconstitution behaviour when the sachet is dosed into water — confirmed per project.
US structure-function statements
- Supports healthy immune functionStructure-function (DSHEA)
- Supports overall wellness and vitalityStructure-function (DSHEA)
Structure-function statements must appear with the FDA disclaimer in the same field of vision on the label. % Daily Value (DV) based on FDA 21 CFR 101.9.
Wording to avoid on pack copy
- No disease claims — this product is not intended to diagnose, treat, cure, or prevent any disease.
- Structure-function claims must be accompanied by the FDA disclaimer: 'These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.'
- No certification promises on pack until confirmed per project and batch documentation.
- No guaranteed shelf-life on pack until confirmed with stability data.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. Structure-function claims are permitted under DSHEA (21 USC §343(r)(6)). No Daily Value (DV) has been established for maitake extract under FDA 21 CFR 101.9.
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Studies & evidence
External peer-reviewed sources and regulatory opinions. Citations only — DAT does not endorse the publishers.
EFSA Panel on Nutrition, Novel Foods and Food Allergens·EFSA Journal·2021
He X, Wang X, Fang J, et al.·Food Chemistry·2017
Zhang Y, Li S, Wang X, et al.·International Journal of Biological Macromolecules·2019
- [04] Polysaccharides from Grifola frondosa: a review of their extraction, structure, and bioactivities
Chen Y, Xie MY, Nie SP, et al.·Carbohydrate Polymers·2018
- [05] Commission Regulation (EU) 1881/2006 setting maximum levels for certain contaminants in foodstuffs
European Commission·EUR-Lex·2006
EFSA·EFSA Journal·2012
Product concepts featuring Maitake Extract
Private-label product concepts where Maitake Extract appears in the formula. Each opens to a product brief and quote route.
Energy Mushroom Gummies
Private label energy mushroom gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Maitake Mushroom Gummies
Private label maitake mushroom gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Mushroom Blend Gummies
Private label mushroom blend gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Mushroom Complex Gummies
Private label mushroom complex gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Reishi Gummies
Private label reishi gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Rise & Shine Mushroom Gummies
Private label rise & shine mushroom gummies for supplement brands. Pectin-based, target-market reviewed manufacturing.
Synergies & conflicts
Pairs well with
Maitake pairs well with other mushroom extracts (reishi, lion's mane, shiitake) for broad-spectrum mushroom blends. Vitamin C and zinc are common co-formulated nutrients for immune support positioning.
Care when combining with
No known formulation conflicts with common gummy ingredients. Standard polysaccharide extracts are compatible with pectin and gelatin gummy bases.
Similar ingredients
Ingredients that frequently sit alongside this one in private-label supplement briefs.

Aloe Vera
Aloe Vera (Aloe barbadensis) is a succulent plant whose inner gel is used in food supplements for its hydrating and soothing properties. As a botanical on the EU on-hold list, it carries no authorised health claims under Reg. 432/2012. Brands typically position it around general wellness, digestive comfort, and skin hydration, often co-formulated with Vitamin C or probiotics for claim support.

Artichoke
Artichoke (Cynara scolymus) is a botanical ingredient used in dietary supplements for its traditional association with digestive and liver function. It is one of the most familiar and commercially understood botanical actives across EU and US markets. As a botanical on the EU on-hold list, no authorised health claims are currently permitted under Reg. 432/2012.

Arugula Extract
Arugula extract is a botanical ingredient derived from Eruca sativa leaves, used in gummy and sachet formats for green superfood and daily wellness positioning. It is a botanical on the EFSA on-hold list with no authorised health claims under Reg. (EU) 432/2012. Any claim coverage must come from co-formulated nutrients.

Ashwagandha
Ashwagandha (Withania somnifera) is a traditional Ayurvedic root used historically for stress, vitality, and sleep. In gummy formats it is most commonly positioned within stress-and-calm or sleep stacks. Ashwagandha sits on the EFSA "on-hold" list of botanical claims, with no authorised EU health claims of its own; substantiated claim wording in Ashwagandha gummies typically derives from co- formulated nutrients such as Magnesium and Vitamin B6.

Bacopa Extract
Bacopa Extract (Bacopa monnieri) is a botanical ingredient traditionally used in Ayurvedic wellness systems. In private-label gummy manufacturing, it is positioned for cognitive support, memory, and stress resilience. Bacopa has no EFSA-authorised health claims under Reg. 432/2012; claim coverage for cognitive function relies on co-formulated nutrients such as Vitamin B6, B12, or Iron.

Bamboo Extract
Bamboo extract is a plant-derived ingredient standardised for silica content, sourced from Bambusa vulgaris. It is used in gummy and sachet formulations as a natural source of silicon, a mineral involved in connective tissue structure. Under applicable claims framework, bamboo extract carries no authorised health claims; brands typically co-formulate with Biotin, Zinc, or Vitamin C for hair, skin, and nails positioning.
Adjacent reading
Pairings, resource guides and blog notes most often associated with Maitake Extract on DAT Supply briefs.
Common pairings
Ingredients that frequently co-formulate with Maitake Extract.
Develop a formula featuring Maitake Extract
A ready white-label formula exists — open a product brief, or talk to our team to align the launch plan.